W. Bryan Smith, PhD

Data, AI &
the Science
Between

Building applications at the intersection of AI, ML, and the data integration systems that connect them to business-critical decisions. Expertise in managing, and extracting value from, high-dimensional messy data where privacy and compliance are not optional.

W. Bryan Smith

Background


I'm a multidisciplinary executive with strong IC capabilities, at my best when I can lead a team by being part of the day to day work we execute together. My lifelong interest in learning systems has taken me through computational neuroscience, data science, machine learning engineering, and executive leadership roles across many different industry domains. PhD from Caltech in neuroscience, where I studied mechanisms of neural coding in real and artificial neural networks. That broad, rigorous training — designing experiments, building models from first principles, communicating findings clearly — has shaped everything I've done since.

I've held technical and executive roles across biotech, healthcare, gaming, market research, and enterprise retail. Currently Co-Founder and CTO at Earthineering. Previously CDO at Sequoia, led identity, interoperability, and AI for Walmart Health & Wellness, co-founded Myia Health (a predictive health monitoring platform), and served as Chief Scientist at PokitDok.

For engineering fun, I build things outside of work too — four independent web products, each addressing a different problem I cared enough to solve. I am an avid photographer, focusing on landscapes, macro, and abstract imagery. And I spend a lot of time on trails, both shoes and wheels.

Selected roles


2024 – Present

Co-Founder & CTO

Earthineering

SMRs for process heat to efficiently generate hydrocarbons (like jet fuel) from carbohydrates (like agriculture waste products). Leveraging ML and AI for process automation, regulatory document parsing and responses, high-dimensional site selection strategies.

2022 – 2025

Group Director, Infrastructure & AI

Walmart Global Tech

Led identity, interoperability, information management, and AI for WMT Global Tech. Focused on entity resolution across regulatory boundaries at scale. Deployed Privacy-Enhancing Tech to accommodate business-critical analytics across domains.

2017 – 2022

Co-Founder & CTO

Myia Labs

Built an intelligent health platform for remote monitoring and engaging patients with chronic conditions. Reduced unplanned hospitalizations by >50% in a remotely managed population using custom predictive models.

2012 – 2018

Chief Scientist

PokitDok

Healthcare transaction platform — consumer marketplace, claims, provider networks, pricing intelligence. Acquired by Change Healthcare.

1998 – 2004

PhD, Neuroscience

California Institute of Technology

Molecular and cellular neurobiology. Local control of synaptic strength via dendritic protein synthesis.

2013-2015

Director, Data Science and Infrastructure

Sapient

Built the global data science practice at Sapient, acquired by Publicis. Large scale analytics on retail data (for Target and other large enterprises).

What I work with


AI & Machine Learning

Machine learning, statistical modeling, NLP, computer vision, recommendation systems, predictive analytics. From Bayesian networks to transformer architectures.

PythonGraphsTorchScikit-learnNLPComputer Vision

Data & Infrastructure

End-to-end data strategy and implementation: pipelines, warehousing, governance, APIs, integrations. Building data organizations from the ground up.

Cloud InfraSparkPostgresKafkaAirflow

Visualization & Communication

Interactive data visualization, scientific communication, translating complex technical work for executives and stakeholders.

PlotlyBokehJupyterD3Javascript

Interests


Photography

Landscapes, macro, and abstract photography — often inspired by my home state of California. My gallery lives at picgraf.com.

Trail Running

The best way to think through a hard problem is on a trail with no cell service.

Get in touch